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If I have a normal head MRI, what are my chances of still having MS?


Sent to Health Experts June 15, 2005 4:22 p.m.

I have had numbness in one eye for approximately 8 weeks. I have had a normal MRI of the head. One VER came back abnormal, a second came back normal. I have a few of the other symptoms of MS (Extreme fatigue, bowel difficulties, depression, sexual dysfunction) My doctor tells me I do not have MS, but will not do further testing. Should I persue the possibility of MS further or trust him?
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June 15, 2005 4:49 p.m. (26 minutes and 42 seconds later)
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Hi Jeff

Since diagnosing MS can be very difficult, a neurologist who specializes in treating MS should evaluate your symptoms. As many as 10% of people diagnosed with multiple sclerosis actually have some other condition that mimics MS. Examples of other conditions that masquerade as MS include inflammation in the blood vessels, multiple strokes, vitamin deficiency, lupus, or brain infection. Sometimes stress-related disorders can lead to a misdiagnosis of MS.

An accurate diagnosis is based on your medical history and a neurological examination (examination of the function of the brain and spinal cord) using various tests. A lot depends on the skill of the doctor in asking the right questions to uncover information and to properly evaluate the signs and symptoms of a malfunctioning brain or spinal cord.

In addition to a thorough medical history and examination, a variety of specialized procedures are helpful -- although not always necessary -- to accurately diagnose MS. These include imaging techniques, such as MRI, spinal taps (examination of the cerebrospinal fluid that runs through the spinal column), evoked potentials (electrical tests to help determine if MS has affected a person's sensory nerve pathways), and laboratory analysis of blood samples.

There is no single test that is proof-positive for diagnosing multiple sclerosis. However, there are accepted criteria for making the diagnosis, but even this system is imperfect.

Since diagnosing MS can be very difficult, a neurologist who specializes in treating MS should evaluate your symptoms. As many as 10% of people diagnosed with multiple sclerosis actually have some other condition that mimics MS. Examples of other conditions that masquerade as MS include inflammation in the blood vessels, multiple strokes, vitamin deficiency, lupus, or brain infection. Sometimes stress-related disorders can lead to a misdiagnosis of MS.

An accurate diagnosis is based on your medical history and a neurological examination (examination of the function of the brain and spinal cord) using various tests. A lot depends on the skill of the doctor in asking the right questions to uncover information and to properly evaluate the signs and symptoms of a malfunctioning brain or spinal cord.

In addition to a thorough medical history and examination, a variety of specialized procedures are helpful -- although not always necessary -- to accurately diagnose MS. These include imaging techniques, such as MRI, spinal taps (examination of the cerebrospinal fluid that runs through the spinal column), evoked potentials (electrical tests to help determine if MS has affected a person's sensory nerve pathways), and laboratory analysis of blood samples.

Here are the accepted criteria for diagnosis of MS

  • Onset usually occurs between 15 and 60 years of age
  • Symptoms and signs indicating disease of the brain or spinal cord
  • Evidence of two or more lesions upon examination by MRI scan
  • Objective evidence of disease of the brain or spinal cord on doctor's examination
  • A course following one of two patterns: two or more episodes lasting at least 24 hours and occurring at least one month apart, or a progressive course of signs and symptoms over at least six months
  • No other explanation for the symptoms

MRI is the best test to view the changes caused by MS. The precise image produced by MRI gives the neurologist clear evidence of scar tissue in the deep parts of the brain or spinal cord that is characteristic of MS.

However, abnormal spots on the brain MRI can be caused by other conditions, so before making a diagnosis your doctor will consider all information including your symptoms and scan results. Similar lesions can be seen in elderly people or people with migraine headaches or high blood pressure.

Also, a normal MRI does not absolutely rule out a diagnosis of MS. About 5% of patients who are confirmed to have MS on the basis of other criteria, do not have lesions in the brain on MRI. These people may have lesions in the spinal cord or may have lesions that cannot be detected by MRI.

Performing a spinal tap to examine the cerebrospinal fluid may be helpful in diagnosing MS in some people, but it is no longer considered necessary in all instances.

Experienced specialists will be able to determine if you need this test to confirm a suspected diagnosis of MS, particularly if your history and examination suggest the presence of the disease. Abnormalities that may appear in the cerebrospinal fluid can be very helpful in establishing a diagnosis but, like other tests, spinal taps are not foolproof in diagnosing MS.

Electrical tests of the nerve pathways, known as evoked potentials, are very helpful in confirming whether MS has affected the visual, auditory, or sensory pathways. These tests are done by placing wires on the scalp to test the brain's response to certain types of stimulation, such as watching a pattern on a video screen, hearing a series of clicks, or receiving electrical impulses in your arm or leg.

Your doctor may order a blood test to help rule out conditions that mimic (imitate) multiple sclerosis, but the presence of MS cannot be detected in the blood.


http://my.webmd.com/content/article/57/66113.htm?printing=true

I hope the above research will help you to make your decision. Please come back if you have more questions.

Kerry



Edited by dahlilahblue on June 15 2005 at 4:50pm
PictureKerry  -- Nurse (RN) -- 99% Positive Feedback on 3873 Health Accepts
35 years in Nursing: OB/GYN, Peds, Oncology, hospice, Ortho, Neuro, Addiction, Recovery, Geriatrics

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