Hello,
Vagifem is a estrogen cream and will increase the vascularity of the vaginal skin and help with your symptoms. So this is an appropriate drug in your case. It seems most of your symptoms are due to atrophic vaginitis, and this may be complicated by Lichen sclerosis. This occurs due to lack of estrogens. Presence of fissure is also consistent with lichen sclerosis. However a biopsy is required to make a definitive diagnosis and to rule out a cancer. And if on physical examination of vagina, cancer is not a possibility, then biopsy would be unnecessary as the treatment of lichen sclerosis remains the same i.e. estrogens. Also you may benefit from oral conjugated estrogens eg. Premarin. So you may discuss this option with your gynecologist.
Regards.
dr. G
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