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my wife is taken zoloft but its not helping the prouble

Sent to Health Experts December 15, 2005 12:10 p.m.

My wife is taken zoloft, but its not helping the prouble she has teking it for 3yrs now. does your body get use to it after were it does not help anymore?

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Female , Age: 46

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December 15, 2005 12:41 p.m. (30 minutes and 41 seconds later)

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Clinical use of most of the anti-depressants of all classes is usually based on empiric effect. That is, one starts the drug and watches the effect on depression. The drug is increased until side-effects appear, or the depression is treated. There are a few of the anti-depressants which do have blood levels available, but there are only a few. Consequently, if the depression appears to be increasing it certainly would make sense to increase the dose and watch the effect(vs. side-effects). There doesn't appear to be major tolerance with long-term use.

However, on the other hand people have experienced a decreased efficacy with long term use, and have tried many things in consultation with their doctors, please read the link below in details for the alternative various people have tried:
http://www.dr-bob.org/babble/20021122/msgs/129427.html

Please remember to accept the reply if you find it useful. A BONUS and a positive rating would be duly appreciated,
regards
Dr. Gupta

Gaurav Gupta -- Doctor (MD) -- 98% Positive Feedback on 4604 Health Accepts
Physician, online medical researcher, & will try to listen and understand you

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