Hi Customer (name blocked for privacy)
I would lean toward the fever being because of your wifes sinus issues. However, I cannot tell you that for sure. What you can do is ask the doctor to run a blood test for white cell count, and possibly a blood culture test to see if any bugs are growing in her blood stream. I would also ask for a culture to be done of the nasal drainage to see what is growing there now that she's been on medicines for several weeks.
I'm assuming you've been seeing an ENT for this doctoring. It might be time to ask for a consult to an infectious disease specialist as well. They may know of something new that can be tried, or think of something the other doctors haven't.
I am here for you if you have more questions, and I sincerely hope your wife feels better real soon.
Kerry
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Kerry, RN
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