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I am a 46-year-old pre-menopausal female.


Sent to Health Experts May 09, 2006 4:17 p.m.
I am a 46-year-old pre-menopausal female. I have a 7mm right-sided pituitary adenoma. A neuroendocrinologist diagnosed me with "central hypothyroidism" and hypopituitarism. I have low free T4 and TSH despite being on 75mcg. of Synthroid for the last 14 months. A DEXA Bone Densitometry scan performed 10/21/05 IMP: 1.Osteoporosis with T-score -2.7.
                                         &nbs p;                          RESULT              &n bsp;              REF. RANGE
Bioavailable Testosterone, Serum        -     1.2 ng/dL   Adult Females: 1.1 -14.3

Sex Horm Binding Glob, Serum    H       -    135 nmol/L (non-pregnant) 18 - 114

FREE T4                                        L & nbsp;   -      0.8 ng/dL                           0.89 -1.76 ng/dL   

TSH                                         & nbsp;      L     -      0.241 uIU/mL                     0.3 - 3.0 uIU/mL


PTH, Intact                                    H     -      85 P                                  7.0 - 58.0 pg/ml

Calcium-Ionized                                       & nbsp;   9.2 mg/dl    High Normal 10.5            mg/dl
                                         &nbs p;                                         &n bsp;     Low Normal    8.7            mg/dl

Aldosterone, Serum                      H    -     16.9 ng/dL                            1.0 - 16.0 ng/dL

Prolactin                                        & nbsp;       -     12.6 ng/dL                            2.8 - 29.2 ng/dL

Thyroid Peroxidase (TPO) Ab              -      <10 IU/mL                             0 - 34

                                         &nbs p;                            
IGF-1 (BL) (growth hormone)               -     114 ng/mL    Age     Range      Mean      SD
                                         &nbs p;                                         &n bsp;    41-50   118-298     205        60

In May-July of 2004 results of urinary free cortisols were 72 (H), 23 & 20 with a normal being between 0-50. In 09/04 a Free cortisol urine of 9.5 ug/24hr normal 10-34, Free Cortisol Urine 1.0 ug/dL, Free Cortisol/Creatinine Ratio 17ug/g norms between 9 - 32. Also in 09/04 the 17-HYDROXYCORTICOSTEROIDS, URINE result was <1.0 mg/24h norms between 2 - 6, 17 - Hydroxycorticosteroids, Urine <0.1 mg/dL, 17-Hydroxycorticosteroids/Creatinine Ratio result <1.7 mg/g with norms between 1.6 - 3.6.

In May, 2004 I had an ACTH level of 88, 02/24/06 result of 7pg/mL (5-27).

I have no pituitary specialists in my area and have been without health insurance, which fortunately will change on July 1, 2006.

I was wondering what your thoughts are on my lab results and where and how do I get proper help. Also what do you think the elevated Intact PTH level may indicate in correlation with my ionized calcium results? Thank you for any input you may have.



My calcium levels are pretty consistently in the upper range of normal, my potassium level on 02/24/06 was 5.3 H mnol/L (3.5 -5.1), Sodium 135 L mmol/L (136-145).


Optional Information:
Female

Already Tried:
while i still had medical insurance i made a trip to California and was tentatively scheduled to have surgery. I had all pre-op testing, met with the neuroendocrinologist and pituitary neurosurgeon several times. I spent 2 weeks there and the Friday before the Monday of the scheduled surgery the endo said that he wanted to wait on surgery for more testing...that he thought my problem was just Growth Hormone deficiency
Customer (name blocked for privacy)
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Answer
May 09, 2006 4:44 p.m. (26 minutes and 57 seconds later) 		ACCEPTED Check Mark
I'm going to reference my lab text so I get a clear picture, I should have an answer for you soon.

__________________
I hope my information is helpful. If you have more questions, just ask! I will gladly help, otherwise please click "accept".
Positive feedback and any bonus would be appreciated. Thank you, Christy
PictureChristy Hammond  -- Bachelor of Science in Nursing -- 100% Positive Feedback on 868 Health Accepts
I am self employed doing medical research for patients on their conditions and treatment options.
Reply
Sent May 09, 2006 5:31 p.m. (46 minutes and 56 seconds later)
Relist:
Christy Hammond said that she would need to reference her lab text information and that she should have some information for me soon. I look forward to hearing from her.

Customer (name blocked for privacy)
Customer (name blocked for privacy)
Info Request
May 10, 2006 1:23 a.m. (7 hours and 52 minutes later) 		REPLIED to Info Request Check Mark
Do you know your phosphate levels?

Also, I did not see your HGH results.

Edited by cch771 on May 10 2006 at 1:37am

__________________
I hope my information is helpful. If you have more questions, just ask! I will gladly help, otherwise please click "accept".
Positive feedback and any bonus would be appreciated. Thank you, Christy
PictureChristy Hammond  -- Bachelor of Science in Nursing -- 100% Positive Feedback on 868 Health Accepts
I am self employed doing medical research for patients on their conditions and treatment options.
Reply to Christy Hammond
Sent May 10, 2006 3:00 p.m. (13 hours and 37 minutes later)
There is an Alk. Phosophatase level result of
100 IU/L (25-150). Also Alkaline Phos. Isoenzymes:            Result Ref. Range
        Liver fraction 23%L (26-86)
        Bone           66%   (11-68)
        Intestinal     11%   (0-16)

Reticulocyte Ct.        0.4% L (0.5-3.0)

By HGH I presume you are referring to Growth Hormone. The neuroendo in CA measured that as IGF-1 (BL) and the result was 114 ng/mL. The ref. range was charted by age, mine being as follows:

AGE           RANGE      MEAN       SD

41-50years   118-298      205       60

(My result 114 ng/mL)

Hope this helps and look forward to hearing from you. thanks.
Customer (name blocked for privacy)
Answer
May 11, 2006 7:49 p.m. (1 day and 4 hours later)
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PictureChristy Hammond  -- Bachelor of Science in Nursing -- 100% Positive Feedback on 868 Health Accepts
I am self employed doing medical research for patients on their conditions and treatment options.

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