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What does Lupus and Rh negative have in common?
Sent to Health Experts June 10 09:26 PM

Do the two have the same antigens? I am Rh negative, I dont remember getting my second shot after I gave birth. Now I have some symptoms of Lupus, I tested borderline positive on a ana test. But my doctor dosent seem bothered by it. It would completely explain the pain that I have been going through for the past 3 years since I first got pregnant. Could the RoGram shot I received make me have signs of Lupus? and what happens to a person in future if they do not get that second shot, or what if I was not rh negative, but it was actually just lupus that my obgyn discovered in the test. I also have xrays that show infamation, but the inflamation test was negative, why is that? Please advise...

 

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Male , Age: 26

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June 11 11:09 PM (1 day and 1 hour later)
         
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plus I am female, I dont know why it says male, lol.
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June 12 2:55 AM (3 hours and 45 minutes and 34 seconds later)
         
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Hello, sorry for the delay! I am so sorry to hear what you have been through! I will be happy to help relieve, at least, your confusion.

The rh factor is a way to type blood based on the rhesus antigen which may or may not be found on the surface of red blood cells. Those with Rhesus Antigens are typed Rh positive, those without are typed Rh negative.

Because you are Rh negative, there is a risk if you carry an Rh positive fetus. When/if the babies blood enters yours (which occurs naturally in some pregnancies or may happen during amniocentesis, an abortion or miscarriage), your blood would sense it as foreign and create antibodies.

These antibodies would remain in your blood for life, and would pass through the placenta, in any future preganacy. This would cause destruction of red blood cells in any Rh positive fetus, and have serious consequences.

The Rho gam is a synthetic antibody and, given at 28 weeks and again at birth, will prevent the body from forming the (permenant) natural antibodies.

If you are concerned that you did not receive your second shot, and do not believe your Physician's reassurance that it was given, you should request your Medical Records. For more information on Rh incompatability in pregnancy, go to:
http://www.marchofdimes.com/professionals/681_1220.asp

An Rh positive woman receiving Rhogam may have a reaction due to destruction of red blood cells. This is an acute reaction, not something she would feel for several years.

In any event Lupus would not cause you to test Rh negative, if you are Rh positive.

The ANA test has a very high rate of false positive results, for many reasons. Rhogam may produce a false positive test result.

Rhogam has not been linked causally to Lupus. If you did not receive the second shot, the risk is to future pregnancies. Your body would overcome the small amount of fetal blood, with few if any physical effects, and then pose a risk to a RH+ fetus.


The connection between the Lupus and the Rh factor is in the test interference. Production of Rh antibodies, or the injection of Rhogam, doesn't cause Lupus, or symptoms of Lupus.

You did not go into your symptoms, but you mentioned a great deal of pain. I am very sorry that you have faced this pain and uncertainty for so long. I hope this answer cleared up some confusion, and that you find an answer to the bigger question (why am I in pain) very, very soon.   

Good luck to you.


I hope my information is helpful. If you have more questions, just ask! I will gladly help, otherwise please click "accept".
Positive feedback and any bonus would be appreciated. Thank you, Christy
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