Handedness runs in families, although even when both parents are left-handed, there is only a 26% chance of their child being left-handed. Thus, it is clear that genetics is not the only cause. Handedness must also be influenced by some of the other theories as well. here.
Take a look at this:
http://64.233.161.104/search?q=cache:lM3MMdteSNMJ:dictionary.laborlawtalk.com/southpaw+southpaw+genetic&hl=en&gl=us&ct=clnk&cd=3
It is an interesting subject for me as well. My husband is right handed, I am left handed, my first daughter is left handed, my second daughter is right handed and my third daughter is left handed but a true ambidextrous as well. Quite fascinating, isn't it?
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