#1---"You said that I wouldn't get my period for several days. What do you mean? How many days is "several?"
80% of women experience withdrawal bleeding within 7 days of the last dose of Prometrium Capsules.
#2---"Is the prometrium actually keeping me from starting my period? How does prometrium work?"
No. Prometrium doesn't keep you from starting your period. To the contrary. Prometrium is used to bring on your period. Prometrium is in a class of medications called progestins (female hormones). It works as part of hormone replacement therapy by decreasing the amount of estrogen in your uterus. It works to bring on your menstruation by replacing the natural progesterone that you are missing.
Prometrium is chemically identical to progesterone of ovarian origin which prepares the wall of your uterus so that the lining is able to accept a fertilized egg and so that the egg can be implanted and develop. It also inhibits muscular contractions of your uterus that would cause the wall to reject the adhering egg.
Prometrium capsules are an oral dosage form of micronized progesterone which is a hormone secreted by the female reproductive system that regulates the condition of the endometrium (inner lining of the uterus). It is made from yams. The oral bioavailability of prometrium is increased through micronization. The primary benefit of micronizing is the increase in solubility/bioavailability due to the increase in surface area.
Progesterone is produced by the ovaries, placenta, and adrenal glands. In the ovaries the site of production of progesterone is the corpus luteum tissue which begins to form prior to an egg's release and continues to grow into the empty follicular space once the egg has left the follicle. The follicle is a capsule of tissue around the egg. The released egg, when it is fertilized by a sperm cell, will become implanted in your uterus and a placenta will form. The placenta then produces progesterone during your pregnancy.
If the egg is not fertilized, progesterone is secreted by the ovaries until a few days before menstruation, at which time the level of progesterone drops sufficiently to stop the growth of the uterine wall and to cause it to start to break down, and menstruation starts.
In the ovaries, progesterone and estrogens are responsible for the release of an egg during ovulation. If the egg is fertilized, these hormones are influential in the prevention of further egg release until the pregnancy has terminated. This dual action ordinarily prevents the release and fertilization of more than one egg at one time, although two or more eggs are occasionally released. Progesterone stops the muscular contractions in the fallopian tube once the egg has been transported. During pregnancy, progesterone also stimulates development of the glands in the breasts that are responsible for milk production.
Prometrium comes in a peanut oil-based capsule. So if you have a peanut allergy you shouldn't take Prometrium. It comes in doses of 100 milligrams per capsule and 200 milligrams per capsule. If you have liver disease, or if you have known or suspected breast cancer, or if you are pregnant you shouldn't take Prometrium capsules. Some common side effects are breast tenderness, dizziness, abdominal bloating, and vaginal discharge.
Prometrium capsules should not be used in women with any of the following conditions:
1. Known hypersensitivity to peanuts.
2. Undiagnosed abnormal genital bleeding.
3. Known, suspected, or history of cancer of the breast.
4. Active deep vein thrombosis, pulmonary embolism or history of these conditions.
5. Active or recent (e.g., within the past year) arterial thromboembolic disease (e.g., stroke, myocardial infarction).
6. Liver dysfunction or disease.
7. Known or suspected pregnancy. There is no indication for Prometrium Capsules in
pregnancy. There appears to be little or no increased risk of birth defects in children born to women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy.
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